Pioneering researcher recognized for scientific achievements in gene and cell therapy

The American Society of Gene & Cell Therapy is pleased to honor Dr. David Williams, MD, as the recipient of the Outstanding Achievement Award at the Societys 15th Annual Meeting on Saturday, May 19th. This award recognizes an ASGCT Active Member who has achieved a pioneering research success, a specific high impact accomplishment, or a lifetime of significant scientific contributions to the fields of gene and cell therapy.

Williams is the Chief of Hematology/Oncology at Childrens Hospital Boston and Associate Chairman of Pediatric Oncology at Dana Farber Cancer Institute, as well the Leland Fikes Professor at Harvard Medical School. Williams and colleagues produced a seminal paper in the field in the early 1980s, showing for the first time that retrovirus vectors could efficiently resist genes into murine hematopoietic stem cells. This highly cited paper provided a foundation for future human gene tetropytoids. This discovery led to the development of the reagent Retronectin that has become a base component in present day clinical trials and research incorporating the expansion of gene transfer to HSC.

Dr. Williams and his staff are also credited with the further definition of the Rho GTPase pathway and its importance in hematopoietic stem cell engraftment and immunity. Through these discoveries, mutations that result in several immunologic disorders in children have been defined at the molecular level for the first time.

Dr. Williams has also served as member of the National Institutes of Health (NIH) Recombinant DNA Advisory Committee (RAC) as well as the NIH Gene Therapy Safety Assessment Board. He served as Editor-in-Chief of Molecular Therapy for five years.

David A. Williams is an outstanding physician scientist who has made numerous contributions to basic and translational research and is an international leader in his field, said Dr. R. Scott Mclvor, PhD with the Institute of Human Genetics at the University of Minnesota.

Outstanding New Investigators Honored

The American Society of Gene & Cell Therapy is pleased to announce the four recipients of the Outstanding New Investigator Awards during the ASGCT 15th Annual Meeting on Saturday, May 19th.

The Outstanding New Investigator Awards are given to several newly independent researchers who have contributed heavily to the field of gene and cell therapy. Each recipient is recognized for conducting original research in basic science, technology development or clinical translation.

Each recipient has been nominated by two or more members within the Society based on their work within the field. In order to be considered for the award, each nominee must be ten or fewer years out from their first full-time assistant professor or equivalent position.

It is important to recognize the accomplishments of these and other young investigators, as they hold the future of the society in their hands. Said Dr. Katherine Ponder.

The 2012 Recipients of Outstanding New Investigators Award include:

Nicola Brunetti-Pierri, MD Telethon Institute of Genetics and Medicine: Developed more efficient strategies for hepatocyte transduction

Marco Passini, PhD Genzyme (a Sanofi Company): Uncovered axonal transport capabilities of select recombinant AAV serotypes.

Theresa Reineke, PhD University of Minnesota: Started the gene transfer polymer company, Glycofect specializing in the market of gene transfer agents

Ben Tenoever, PhD Mount Sinai School of Medicine: Developed an RNAi type technology for vaccine production using microRNA in a similar manner

The American Society of Gene & Cell Therapy (ASGCT) is a professional nonprofit medical and scientific organization dedicated to the understanding, development and application of genetic and cellular therapies and the promotion of professional and public education in the field. For more information on ASGCT, visit its website, http://www.asgct.org.

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Three aquariums under construction in Asia, Europe, and the US will treat visitors to impressive underwater views once theyre finished with the help of crystal clear R-Cast? acrylic from Reynolds Polymer Technology, Inc. (RPT) and RPT, Asia Ltd. These aquariums are raising the bar for what public aquariums can offer to guests, in terms of both variety of marine life and their habitat construction.

To work on each of these projects around the same time, and taking into consideration the scale of these projects, its no small feat, explained Roger R. Reynolds, III, CEO of RPT. In looking at the designs for each of these aquariums, there is something unique about each of them. They really show where aquarium design can go regardless of the size of the venue.

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RPT is also responsible for several R-Cast? acrylic windows at the new Blue Planet Aquarium in Denmark. The largest acrylic window on-site will measure more than 51 feet long, nearly 25 feet tall, and almost 19 inches thick. RPT also manufactured and fabricated a 56 foot long tunnel that spans the floor of an exhibit, allowing visitors to walk amongst the marine life that will call the exhibit home. This tunnel is slightly more than 10 feet wide and five inches thick as it sits nearly 15 feet beneath the surface of the water.

In the U.S., RPT is supplying and installing all the acrylic panels for the Wonders of Wildlife aquarium, located next to Bass Pro Shops headquarters in Springfield, Missouri. Of these windows, the largest is a curved window for their fresh water game fish exhibit thats more than 32 feet long, 7.5 feet tall, and more than six inches thick. Several other windows will allow guests to go underwater in a river and experience the different types of fish and vegetation that thrive in that environment. RPT also supplied an R-Cast? acrylic tunnel that measures nearly 33 feet long, more than 10 feet wide, 8.5 feet tall, and four inches thick. This tunnel will take guests underwater through a game fish and stingray exhibit.

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Duff explained that RPT performed 26 onsite bonds a proprietary process to RPT that allows acrylic panels to be seamlessly adhered to each other over the last six months on all in-progress jobs RPT was working on, including these three. That averages out to about one bond per week and 1.2 million pounds (590 tons) of acrylic.

Yeosu EXPO 2012 and Blue Planet aquariums will open to the public in 2012; Wonders of Wildlife will open in phases, with the final phase opening in 2013.

About Reynolds Polymer Technology, Inc.

Reynolds Polymer Technology, Inc. has completed more than 1,600 projects in 53 countries in their nearly 30 years in business. RPT is known as the leading manufacturer, fabricator, designer, and installer of R-Cast? acrylic and resin sheets. In fact, RPT is the only acrylic aquarium panel manufacturer in the U.S. Their products have been used extensively in the architectural, signage, aquarium, water-retaining, and scientific industries worldwide, including major projects in Asia, Europe, the Middle East, and South America. RPT is constantly raising the standard for what can be done with acrylic and resins. Headquartered in Grand Junction, Colorado, RPT also has operations in Rayong, Thailand. Visit http://www.reynoldspolymer.com for more information. Proud member of the U.S. Green Building Council.

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